The mission of the Tulane Biostatistics and Bioinformatics Core (TBBC) to support researchers at Tulane University by providing expert guidance and analytical services that transform complex biological data into meaningful insights. We employ cutting-edge bioinformatics tools and biostatistical methods to facilitate the interpretation of large-scale datasets, enabling groundbreaking discoveries and advancements in medical science. Our core specializes in the comprehensive analysis of high-throughput omics data, including genomics, transcriptomics, proteomics, and other emerging fields.

Genomics: Our core offers extensive expertise in the analysis of genomic data, including whole-genome sequencing, exome sequencing, and genome-wide association studies (GWAS). We help researchers identify genetic variants, understand genetic architecture, and uncover the molecular basis of diseases.

Transcriptomics: We provide comprehensive support for transcriptomic analyses, including RNA sequencing (RNA-seq) and single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics with different platforms. Our services encompass, e.g., differential expression analysis, gene regulation studies, and pathway enrichment analysis, network system biology analyses, AI analyses with machine learning, helping to elucidate gene expression patterns and regulatory mechanisms.

Proteomics: Our core is equipped to handle proteomic data analysis, including mass spectrometry (MS) based protein identification and quantification. We assist researchers in identifying protein biomarkers, understanding protein interactions, and studying post-translational modifications, ultimately contributing to the understanding of cellular functions and disease mechanisms.

Other Omics: In addition to genomics, transcriptomics, and proteomics, we offer expertise in metabolomics, epigenomics, and metagenomics and multi-omics analyses at bulk and single cell levels. Our integrated approach allows for the comprehensive analysis of multi-omics data, providing a holistic view of biological systems and facilitating the discovery of novel therapeutic targets.

At the Biostatistics and Bioinformatics Core, we are committed to fostering a collaborative research environment. Our team of experienced bioinformaticians and biostatisticians works closely with investigators to design robust experiments, perform sophisticated data analyses, and interpret results with precision. Through our services, we aim to accelerate scientific discovery and enhance the impact of research conducted at Tulane University.